Serveur d'exploration sur le lymphœdème

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Are we nearly there yet? Coverage and compliance of mass drug administration for lymphatic filariasis elimination

Identifieur interne : 002131 ( Main/Exploration ); précédent : 002130; suivant : 002132

Are we nearly there yet? Coverage and compliance of mass drug administration for lymphatic filariasis elimination

Auteurs : Neal D. E. Alexander

Source :

RBID : PMC:4321021

Descripteurs français

English descriptors

Abstract

Lymphatic filariasis has been targeted for elimination by 2020, and a threshold of 65% coverage of mass drug administration (MDA) has been adopted by the Global Programme to Eliminate Lymphatic Filariasis (GPELF). A recent review by Babu and Babu of 36 studies of MDA for lymphatic filariasis in India found that coverage, defined as receipt of tablets, ranged from 48.8 to 98.8%, while compliance, defined as actual ingestion of tablets, was 22% lower on average. Moreover, the denominator for these coverage figures is the eligible, rather than total, population. By contrast, the 65% threshold, in the original modelling study, refers to ingestion of tablets in the total population. This corresponds to GPELF's use of ‘epidemiological drug coverage’ as a trigger for the Transmission Assessment Surveys (TAS), which indicate whether to proceed to post-MDA surveillance. The existence of less strict definitions of ‘coverage’ should not lead to premature TAS that could impair MDA's sustainability.


Url:
DOI: 10.1093/trstmh/tru204
PubMed: 25575555
PubMed Central: 4321021


Affiliations:


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